Gc-MAF is a naturally occurring protein. There is much evidence of its effectiveness and vital role in nurturing the health of vital human organs. Studies relate that VDTP/Gc-MAF can be successfully used to treat autism spectrum disorder and provide relief to patients.

The use of (VDTP/Gc-MAF) has demonstrated positive effects in the treatment of autistic children. VDTP/Gc-MAF is an endogenous glycosylated vitamin D binding protein, or Vitamin D Transport Protein(VDTP) that is majorly responsible for macrophage cell activation.

Autism and autism spectrum disorders

Autism & autism spectrum disorders (ASDs) are complex heterogeneous neurodevelopmental conditions caused by the interaction of genetic & environmental factors. Autism spectrum symptoms include:

  • Dysfunctions in communication skills & social interactions
  • Repetitive, restrictive & stereotypic verbal/non-verbal behaviour.
  • Difficulties reading social behavior
  • Problems making eye contact
  • Understanding someone else’s perspective
  • Not understanding boundaries
  • Talking too loudly
  • Lacking in basic speech and conversational skills
  • Problems with small talk
  • Heightened senses
  • Stimming

The scientific explanation for the underlying condition can be described as recent observations finding increased N-acetylgalactosaminidase (Nagalase) levels in the blood of children during autism spectrum tests. This increase in Nagalase[enzyme] catalyzes the deglycosylation of the Gc protein, which in effect deactivates these fighter cells and prevents them switching to regulatory protein state of Gc Macrophage Activating Factor (VDTP/GcMAF). This clinical condition diminishes the body’s macrophage activating capacity, which results in a compromised immune system, causing further health issues and the bodies inability to fight toxins in the way a healthy immune system can.

Conventional Management of Autism

Autism is a complex issue and behavioural as well as environmental factors can into play. More than half of children in the US diagnosed with ASD are simply administered psychoactive drugs or anticonvulsants, which seems to be exacerbate the issue and cause further health and psychological problems. The most common drug classes are stimulants, antidepressants, and antipsychotics. There is little research about the effectiveness or safety of drug treatment for adolescents and adults with ASD. Essentially, traditional management of autism does not address the cause of the disease and only attempts to treat the symptoms.

VDTP/GcMAF treatment seems to have better effects on autistic children; however, further studies are needed to understand the cellular & molecular pathways involved in this therapeutic effect.

During the past decade, many doctors have claimed that VDTP/GcMAF are effective in the fight against immunity disorders, such as anything from cancer to autism by boosting the human immune system. James Jeffery Bradstreet was an avid believer. In posts on his researches and blogs, he shared some VDTP/GcMAF patients’ anecdotes. In 2012, he gave a presentation in England in which he described giving VDTP/GcMAF injections to 40 autistic patients [16months-21 years] and its positive effects. His research accounts for how GcMAF/VDTP supplement & sublingual immunotherapy showed significant health benefits to autistic patients.

How does Gc-MAF/VDTP Treatment Work?

By now, we know that VDTP/Gc-MAF is a naturally occurring protein. Healthy Globulin component Macrophage Activating Factor, or VDTP/GcMAF, is removed, concentrated and injected back into a sick patient. The VDTP/Gc-MAF Treatment has shown significant results in curing chronic disorders, Cancer and ADS.

Individuals with Autism witness altered immunity and abnormalities involving cytokines, immunoglobulins, inflammation and cellular activation.

Alterations in immune cells such as macrophages or natural killer cells have been found in individuals with autism.

Avid researches suggest VDTP/GcMAF therapy for the treatment of Autism. During the clinical process, second-generation high-dose VDTP/GcMAF immunotherapy is administered to overcome immune system dysfunction. This plays an integral role to eliminate and reduce the root causes behind autism spectrum symptoms.

Some Clinical Effects of VDTP/Gc-MAF supplement on Autistic Children:

GcMAF normalizes endocannabinoid system gene dysregulation in blood monocyte-derived macrophages (BMDMs) in autistic children.

study evaluated the VDTP/GcMAF effects on NAPE-PLD (N-acyl phosphatidylethanolamine phospholipase D), a protein-coding gene. VDTP/GcMAF treatment significantly increased gene expressions both NAPE-PLD, before and after VDTP/GcMAF treatment in autistic BMDMs.

GcMAF affected CB2R protein levels in BMDMs

VDTP/GcMAF has been found to reduce the protein levels for cannabinoid receptor type 2[CB2R] in BMDMs from autistic children when treated in healthy controls. Further analysis showed a substantial decrease in CB2R protein levels in VDTP/GcMAF treated BMDMs from autistic children compared to untreated macrophages.

VDTP/GcMAF decreased the protein levels of the alternative activated phenotype M2 macrophage marker.

To learn more about the VDTP/GcMAF effect in cellular activation in macrophages, some studies quantified the protein levels of mannose receptors through a Western blot analysis. The results were a decreased mannose receptor protein level in VDTP/GcMAF treated BMDMs from autistic children compared to untreated macrophages.

For a full description of a real case study of Autism recovery using these methods and more, please refer to this article 

Ending Note:

Autism is considered a multifactorial disease associated with complex genetic & environmental interactions inducing risk factors. Research proves VDTP/Gc-MAF stimulates cAMP formation in human mononuclear cells and inhibits angiogenesis in chick embryo chorioallantoic membrane assay. With the initial findings showing positive effects of VDTP/GcMAF treatment in autistic patients, faith and reliance on this treatment can benefit the patients. At the same time, they await the mainstream pharma giants to elucidate a more reliable cure!

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